A new model for heart valve disease drug discovery

An article published in Experimental Biology and Medicine describes a new model for heart valve physiology. The study, led by Dr. Carla Lacerda, from the Department of Chemical Engineering at Texas Tech University reports that 10% cyclic radial strain on isolated mitral valve anterior leaflets provides a true physiological environment that can be used for mechanistic studies and drug discovery. […]

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ASCO: guidelines released for early detection, treatment of CRC

(HealthDay)—Expert guidance has been provided on the early detection of colorectal cancer and on treatment and posttreatment follow-up; the two guidelines were recently published online in the Journal of Global Oncology. Gilberto Lopes, M.D., from the University of Miami, and colleagues identified and reviewed guidelines and used evidence from cost-effectiveness analyses to develop recommendations on the early detection of colorectal […]

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Finally, people with disabilities will have a chance to tell their stories – and be believed

The draft terms of reference for the royal commission into the abuse and neglect of people with disabilities, released for comment this week, outline the commission’s plan to investigate all forms of violence, abuse, neglect and exploitation of people with disabilities. For too long, these acts of violence and abuse, particularly where they occur in support services, have been referred […]

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An impaired sense of smell can signal cognitive decline, but ‘smell training’ could help

As we age, we often have problems with our ability to smell (called olfactory dysfunction). Older people might not be able to identify an odour or differentiate one odour from another. In some cases they might not be able to detect an odour at all. Odour identification difficulties are common in people with neurodegenerative diseases, including Alzheimer’s disease. In the […]

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Mobilizing the lymphatic system may help combat obesity-induced metabolic syndrome

The search by scientists to find ways to combat obesity continues. Recently, investigators have been exploring whether they can engage the lymphatic system to help regulate obesity-induced inflammation of fat (adipose) tissue and restore systemic metabolic fitness. In a study appearing in he American Journal of Pathology, researchers report that augmenting lymphatic vessel formation in obese adipose tissue via vascular […]

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Experiences of nature boost children’s learning

Spending time in nature boosts children’s academic achievement and healthy development, concludes a new analysis examining hundreds of studies. Ming Kuo, associate professor in the Department of Natural Resources and Environmental Sciences at the University of Illinois and lead author on the Frontiers in Psychology study, says she expected the critical review to lead to more questions than answers. Instead, […]

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Chest CT may be better than PET/CT for HNSCC distant metastasis evaluation

(HealthDay)—As distant metastasis (DM) in head and neck squamous cell carcinoma (HNSCC) is a rare event, computed tomography of the chest may be more cost-effective for evaluation, according to a study recently published in Oral Oncology. Jeffrey C. Liu, M.D., from Temple University in Philadelphia, and colleagues examined the frequency and location of DM at presentation in HNSCC using data […]

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