Team discovers biological markers that could guide treatment for prostate cancer

Genetic alterations in low-risk prostate cancer diagnosed by needle biopsy can identify men that harbor higher-risk cancer in their prostate glands, Mayo Clinic has discovered. The research, which is published in the January edition of Mayo Clinic Proceedings, found for the first time that genetic alterations associated with intermediate- and high-risk prostate cancer also may be present in some cases […]

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Obese mice lose anxiety when ‘zombie cells’ exit their brain

Mayo Clinic researchers and collaborators have shown in mice that obesity increases the level of “zombie” or senescent cells in the brain, and that those cells, in turn, are linked to anxiety. When senolytic drugs are used to clear those cells, the anxious behaviors in the mice dissipate. These findings appear in Cell Metabolism. Senscent cells are just as the […]

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Role of PCSK9 inhibitors in high risk patients with dyslipidemia

Familial hypercholesterolemia (FH) is an inherited autosomal dominant disorder which is characterized by substantially increased Low-Density Lipoprotein Cholesterol (LDL-C) levels. Timely reduction of LDL-C is of paramount importance to ameliorate the risk for CV disease as patients with FH have a significantly higher risk for Cardiovascular (CV) events. Pro-protein Convertase Subtilisin/Kexin type 9 (PCSK9) inhibitors have emerged as a very […]

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Could your Apple Watch spot dangerous A-fib?

(HealthDay)—That shiny new Apple Watch you got this holiday could potentially alert you to heart trouble you didn’t know you had. The watch contains a simple electrocardiogram (ECG) that tracks your heart rhythm and can detect the presence of atrial fibrillation (“A-fib”), an irregular heartbeat that increases your risk for stroke and heart failure. More than 400,000 Apple Watch wearers […]

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