Health: Early Alzheimer’s disease due to high cholesterol
Pay attention to the protection against Alzheimer’s on your cholesterol levels
High cholesterol increases the risk of an early onset of Alzheimer’s disease and may trigger according to the latest findings even with the devastating disorder of the brain.
In the present study, of Emory University found that a high cholesterol level increases the risk for an early onset Form of Alzheimer’s. The results of the study were published in the English journal “JAMA Neurology”.
Diet can protect against Alzheimer’s
There is a connection between of the more common and late-onset Form of Alzheimer’s disease and high levels of cholesterol that has already been established in several studies. Cholesterol in the blood increases the risk for Alzheimer’s significantly, regardless of whether the person Concerned to wear the so-called Alzheimer’s Gene or not. The results of the new study suggest that a healthier diet could help to prevent the onset of memory loss.
Four genes increase the risk of onset of early-Alzheimer’s
There are four genes, which seem to be the risk for an early onset of Alzheimer’s to increase disease, report the researchers. Taken together, these genes make up probably about 14 percent of the 200,000 cases of early of Alzheimer’s disease from onset in the United States, explain the authors of the study. Well over five million Americans suffer overall, Alzheimer’s disease, the disease, however, occurs typically after the age of 65. Since the age of. But between five and ten percent will develop a memory loss that begins in the forties or fifties, add the researchers.
Unfortunately, there is still no cure for Alzheimer’s
Some of the people, which, due to inheritance, particularly high-risk genes for the illness, and suffering-sometimes even after your 30. Age of loss of memory. Tests for the diagnosis of the disease remain relatively subjective, treatments are minimally effective and there is no cure. The researchers hope that they come through a better understanding of the causes and risks of the disease, the development of therapies or the disease can prevent in the future, possibly even completely.
What is the influence of LDL-cholesterol?
But to Gent fully developed therapies for Alzheimer’s disease, there are no options to be Concerned with an increased Alzheimer’s to help risk in their DNA. Therefore, the researchers studied a easier-to-modify risk factor: cholesterol. In particular, they focused on low-density lipoprotein (LDL), which are frequently referred to as unhealthy cholesterol.
The researchers samples, examined the blood and DNA of 2.125 Participating. At 654 of them has Alzheimer’s diagnosed at an early stage. About ten percent of Participants with Alzheimer’s disease in the early stage, wore a Variation of the so-called APOE gene, which is closely associated with the disease. A further three percent contributed according to the study, at least one of three risk genes in. This doesn’t explain the increased risk for early-onset Alzheimer’s disease. A possible explanation lying in the blood cholesterol levels. Men and women with high LDL were independent of their genetic risks of developing an increased risk already at a young age from Alzheimer’s.
The question is whether there is a causal relationship between the level of cholesterol in the blood and Alzheimer’s is risk. The current data can be interpreted to mean that LDL cholesterol plays a causal role, the authors of the study. Eventually, the target sizes of the cholesterol levels must therefore be revised, in order to protect people better against Alzheimer’s. (as)